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Symbol
Name
ID
Ikzf4
IKAROS family zinc finger 4
MGI:1343139
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
decreased T cell proliferation
small intestinal inflammation
enlarged spleen
increased germinal center B cell number
increased T follicular helper cell number
decreased regulatory T cell number
increased T cell number
increased spleen B cell follicle number
increased spleen germinal center number
increased immunoglobulin level
enlarged lymph nodes
increased susceptibility to experimental autoimmune encephalomyelitis
chronic inflammation
granulomatous inflammation
glomerulonephritis
Availability Mouse Genotype
Ikzf4tm1.1Etms/Ikzf4tm1.1Etms *
Foxp3tm4(YFP/icre)Ayr/Foxp3tm4(YFP/icre)Ayr
Ikzf4tm1Djr/Ikzf4tm1Djr  (conditional)
Ikzf4tm1Djr/Ikzf4tm1Djr
Tg(Cd4-cre)1Cwi/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory